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3D Ultrasound Tomography for Breast Cancer Diagnosis
03.07.2018, 09:30 - 10:30
Gebäude 6.42, Raum 001
Hertzstrasse 16
76187 Karlsruhe

A promising candidate for sensitive imaging of breast cancer is 3D ultrasound computer tomography (3D USCT). The main advantages of USCT are simultaneous recording of reflection, attenuation and speed of sound images, high image quality and fast data acquisition. Due to the defined patient positioning and no breast deformation, the volume images of the female breast are reproducible.

Building such a device for clinical practice was not successful for a long time - mostly due to the huge data rate and the time-consuming image reconstruction. Currently, the first 2D systems have become available for clinical evaluation. At KIT we developed and tested the first full 3D USCT system.

The 3D USCT device is equipped with 2041 ultrasound transducers with 2.5 MHz resonance frequency. The acquisition is carried out by sequentially selecting a single emitter, sending a chirp and recording the transmitted and reflected waves with all receivers. Rotational and translational movement of the aperture is applied to enhance the image contrast. Up to 80 GB of raw data is digitized with 480 parallel channels at 12 Bit and 20 MHz sampling frequency. A 3D synthetic aperture focusing technique (SAFT) is applied for reflectivity image reconstruction, which is highly compute-intensive. Parallel reconstructions on a GPU sever enables reconstruction of high resolution breast volumes in 10 minutes.

In a first pilot study ten patients with different lesions were imaged. Speed of sound, attenuation and reflection images of each patient were derived from the raw data. Overlaid volumes of the modalities show qualitative and quantitative information at a glance. The results are promising as the breasts’ tissue structures and cancerous lesions could be identified in the USCT images. A larger study is currently carried out at the University Hospital in Mannheim.

Dr. Nicole Ruiter
Geophysikalisches Institut (GPI)
Hertzstrasse 16
76187 Karlsruhe
E-Mail:webmasterKbu5∂gpi kit edu
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